#Jmol ramachandran plot software#
While computer graphics software greatly aids in the understanding of these structures by displaying them in three-dimensions, the pages of printed scientific journals flatten the structures to a two-dimensional image, with much of the three-dimensional information thus being lost. The widely held impression is that these structures are understood in detail and put to use in research in fact, the structures are hardly discussed at all, especially by biologists lacking a structural background. But structural information is surprisingly still not in the mainstream of biology for the simple reason that three-dimensional structures are often hard to understand, even for a structural biologist. Indeed, a wealth of protein structures has been solved in recent years, and entries in the Protein Data Bank (PDB) now number over 50,000. Beautiful images of three-dimensional structures regularly adorn the covers of Science, Nature and Cell. More than a dozen Nobel prizes have been awarded for achievements in structural biology since solution of the structure of the DNA double helix in the early 1950s was followed by solution of the first protein structures at the end of the same decade. Structural biology has played a central role in fueling the massive advances made by the life sciences in the last few decades.
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